BML-PW0325-0100 100 µl
BML-PW0325-0025 25 µl
Sp100 is an interferon-inducible protein and a major constituent of distinct nuclear domains, known as nuclear dots (NDs) or PML bodies. NDs play a role in autoimmunity, virus infections, and in the etiology of acute promyelocytic leukaemia. SUMO modification of Sp100 has been shown to promote interaction of Sp100 with non-histone chromosomal proteins, suggesting a regulatory role in chromatin organization and in functional interplay between these nuclear bodies and chromatin.
Product Specification
Formulation: Liquid. In PBS containing 0.01% sodium azide.
Immunogen: Synthetic peptide corresponding to aa 292-304 of human Sp100.
Source/Host: From rabbit.
Specificity: Recognizes human Sp100 and SUMO modified Sp100 species.
Application: Immunocytochemistry
Western Blot
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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