ABLAntibody(Y251)

ABL Antibody(Y251)
Cat.#: T1152
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P42684
Mol Weight: 128kDa
Size: 100ug

Description
ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1.

Recommended Applications
WB, ELISA

Applications and Recommended Dilution Factors
WB: 1:10~50
ELISA: 1:1,000

Species Reactivity
Human

Products Data

 
Western blot analysis of anti-ABL Antibody (Y251) in A2058 cell line lysates (35ug/lane). ABL(arrow) was detected using the purified Pab.

Specificity
This ABL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y251 of human ABL.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Alternative Names
ABL2 antibody, ABLL antibody, ARG antibody, FLJ22224 antibody, FLJ31718 antibody, FLJ41441 antibody, Tyrosine-protein kinase ABL2 antibody, Abelson murine leukemia viral oncogene homolog 2 antibody, Abelson-related gene protein antibody, Tyrosine-protein kinase ARG antibody

Description References
Cao, C., et al., Biochemistry 42(35):10348-10353 (2003).
Cao, C., et al., J. Biol. Chem. 278(32):29667-29675 (2003).
Kruh, G.D., et al., Proc. Natl. Acad. Sci. U.S.A. 87(15):5802-5806 (1990).
Kruh, G.D., et al., Science 234(4783):1545-1548 (1986).
Bianchi, C., et al., FEBS Lett. 527 (1-3), 216-222 (2002).