Biological Activity: Highly potent, selective inhibitor of vacuolar H+-ATPases (IC50 = 500 pM as measured in chromaffin granule membranes). Selective over other ATP hydrolyzing enzymes such as F-ATPases, Ca2+-ATPases, Na+/K+-ATPases and plasma membrane H+-ATPases. Synonym Store at -20oC , Desiccate |