ALS2CR2antibody

ALS2CR2 antibody
Cat.#: S1785
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q9C0K7
Mol Weight: 47.03kDa
Size: 100ug

Description
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data 

 

Sample (30ug of whole cell lysate)
A: Hela
10% SDS PAGE
diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using ALS2CR2 antibody at 1:100 dilution.

Specificity
356 - 418 of Human ALS2CR2

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
STRADB antibody, ALS2CR2 antibody, CALS-21 antibody, ILPIP antibody, ILPIPA antibody, MGC102916 antibody, PAPK antibody, STE20-related kinase adapter protein beta antibody, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein antibody, CALS-21 antibody, ILP-interacting protein antibody, Pseudokinase ALS2CR2 antibody