4-2-胺乙基苯磺酰氟盐酸盐

Pefabloc® SC 
分析标准品

Description
Application Recommended concentrations for use are 0.1-1 mM.
Biochem/physiol Actions Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM.
Other Notes Potent and irreversible inhibitor of serine proteases; in contrast to PMSF, it is water soluble and non-toxic1,2; Unaffected by albumin3
Legal Information Pefabloc is a registered trademark of Pentapharm AG, Basel

Properties
grade analytical standard
assay ≥98.0% (HPLC)
mp ~183 °C
storage temp. 2-8°C

Safety
Symbol GHS05
Signal word Danger
Hazard statements H314
Precautionary statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45
RIDADR UN 3261 8/PG2
WGK Germany 3